The revolution of MDMA was televised. The drug had turned from a party/rave drug to a wonder therapy drug with the ability to treat PTSD, depression, and other mental health issues. There are also indications that the substance can help with social anxiety and help you communicate very well. People who use it as a party drug believe it helps you dance well.
From all indications, it seems like MDMA will soon make it into society as a full-blown legitimate therapeutic drug. The substance was recently cleared for the third phase of clinical trials in the United States of America. While this news holds a lot of hope for people who have PTSD, there is not a lot that an average person can unpack from the news. This is because when the drug eventually becomes a treatment for PTSD or mental health issues, it will only be available to those who can afford the treatment or have a serious health condition that requires it.
This does not mean the general public would not get its share of the party drug. People have been microdosing on psychedelics such as LSD, mescaline, and psilocybin for different purposes, from creative to spiritual to recreational. There is nothing to say that people would not microdose on MDMA too.
While it is not as popular as LSD or psilocybin, microdosing MDMA has been going on for a while now. Reports from social media platforms such as Reddit show that many people have tried microdosing on the substance for some time now. There was a particular story by a student in Britain who microdosed on the substance during her exam. While she could get some benefits from the drug, she maintained that these benefits were not worth the hangover she suffered in the following weeks.
A lot of medical research has shown that the frequent use of MDMA has a lot of harmful side effects on the body. Unlike other psychedelics, MDMA is a stimulant in the amphetamine medical class. Its effect on the body differs from what you will experience with a tab of LSD. Another research showed that frequent usage of MDMA can cause heart issues. In this study, the substance was given to 29 participants as ecstasy pills. These 29 participants took high doses of the substance twice a week. At the end of the study, it was realized that 28% of the participants developed faulty hearts, which caused serious heart problems. On the other hand, none of the control subjects have the same issues.
One of the reasons why the substance affects the heart is its action on specific receptors in the heart. Receptors such as 5HT2B are found in high concentrations in the heart, and MDMA is introduced to the body, which triggers the chain reaction that damages the heart valves.
While the studies on the adverse effect of MDMA have focused on a high dosage, there is an indication that frequent use of the drug in microdosing will also cause adverse effects on the human body. For normal doses, people are advised to take it once every few months.
Therefore, the safest guess is that frequent use of the substance can lead to the activation of the 5HT2B receptors in the heart, causing heart diseases, as MDMA is one of the strongest activators of 5HT2B.
Finally, we do not advise microdosing on MDMA regardless of the reported benefits. The best way to use the substance is a normal dose, once in a few months, in a comfortable setting with friends and loved ones around.
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